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Men were given 1 g of L-carnitine orally 3 daily for 3 months

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Specifically, blocking antiporter activity interferes with DCs differentiation from monocyte precursors, but the antiporter activities are not required for LPS-induced phenotypic maturation

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In this Review, we discuss several newly discovered gut microbial metabolic pathways, including the production of trimethylamine and trimethylamine N -oxide, short-chain fatty acids, and secondary bile acids, that seem to participate in the development and progression of cardiovascular diseases, including heart failure