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J Lumin 180:1419

However, the exogenous application of glutathione improved the levels of ascorbic acid, glutathione, and nicotinamide adenine dinucleotide phosphate and the ratios of AsA/DHA, GSH/GSSG, and NADPH/NADP + (Figure 3), indicating that redox cycle activities were strengthened and that these suppressed the ROS generated by Cd toxicity

Duration of Use : Long-term use of glutathione supplements should be monitored by a healthcare professional to avoid potential side effects like stomach upset or reduced zinc levels

Nonetheless, the role of ferroptosis in CNS diseases needs further elucidation, and currently there is no definitive evidence linking CNS diseases with ferroptosis in long-term animal model studies