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Vitamin B7/8 Vitamin B7/8 is known under the name of biotin, which is a prosthetic group of five cellular carboxylases in humans (acetyl-CoA carboxylase 1 and 2 (ACC1, ACC2), propionyl-CoA carboxylase (PCC), 3-methylcrotonyl-CoA carboxylase (MCC), and pyruvate carboxylase (PC)), four of which are located at the outer membrane or in the matrix of mitochondria [103]