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Hence, AuNPs have been specifically designed to have anti-angiogenic effects in diseases where angiogenesis (the growth and extension of blood vessels from pre-existing blood vessels) spins out of control like cancer, rheumatoid arthritis, macular degeneration and obesity [5, 25, 113, 117]

In this experiment, a black wood Y-maze having three arms (35 cm long, 25 cm high and 10 cm broad) with a symmetrical triangular middle region, was employed