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identified differentially expressed genes (DEGs) between thyroid tumors and normal tissues, demonstrating a significant association between ferroptosis and the TME, particularly with tumor immune cells (70)

Various medical conditions, such as Polycystic Ovary Syndrome (PCOS), thyroid disorders, and hyperprolactinemia, are also frequent causes

Infection with SARS-CoV-2 activates caspase-8 (a master regulator of pyroptosis and necroptosis) and RIPK3 to initiate inflammatory cytokines within lung epithelial cells (28)