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Nutrition matters more than ever While GLP-1 drugs suppress appetite, they also create new nutritional challenges

Importantly, this implies that FSP1 may be essential not only in cancer resistance to ferroptosis but also in physiological contexts such as adipose tissue metabolism, where regulation of neutral lipid oxidation is critical for maintaining tissue homeostasis

It distributes widely in the body and is excreted through urine

Macrophages are involved in clearing various forms of dead cells, where SAPE-OOH molecules on the surface of ferroptosis cells act as eat me signals, promoting macrophage phagocytosis (208)

From an interventional perspective, diversified strategies, including psychobiotics, FMT, dietary modification, and exercise provide abundant options for clinical practice