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High Hcy levels are linked to shorter lifespans

Consistent with this, patient-derived xenograft (PDX) models with genetic depletion or enzymatic degradation of GAGs exhibited reduced LDL uptake and impaired tumor growth, reinforcing GAG biosynthesis as a critical determinant of tumor growth by mitigating lipid oxidative stress

Another characteristic of the NutriNet-Sant study was that, compared with other studies, a small proportion (28%) of cohort members were aspartame users, so the study could not look at finer stratification of the amount consumed