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The uptake of GSH (or GSSG) could be through a specific transportersuch as a homologue of CydDC, which is an ATP-binding cassette (ABC)-type transporter that has recently been identified to export GSH and cysteine specifically to the periplasm of Escherichia coli (Pittman et al , 2005)

These models could further be leveraged to investigate if NSC-secreted factors modulate the gut microbiomes metabolic output or vice versa, providing a mechanistic link between the central and peripheral effects observed in our study

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Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy

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