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the body converts it before use

These findings highlighted that ultrahigh-dose methylcobalamin was efficacious in slowing functional decline in patients with early-stage ALS and with moderate progression rate and was safe to use during the 16-week treatment period, the researchers wrote

However, because B12 bound to haptocorrin is not metabolically active, use of only total serum B12 may result in Black patients being incorrectly identified as having a high B12 status

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