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The Journal of Allergy and Clinical Immunology

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These findings underscore the developmental importance of early microbial signals in shaping neural circuits and behavior, processes modulated by molecules such as reelin, which controls dendritic growth and synaptic receptor function in post-natal entorhinal cortex neurons (Hamad et al., 2021b,a, 2024b,a

The following points investigate how these conditions can promote physiological changes necessary for stress tolerance that end up influencing symbiotic establishment or nitrogen fixation (Table 1)