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One of the key players in the NEM stress response is the release of stress hormones like cortisol via the adrenal glands

Lactate and lactate dehydrogenase in cistern as biomarkers of early brain injury and delayed cerebral ischemia of subarachnoid hemorrhage

Hepatic injury generally starts 24 to 72 hours after the ingestion with marked elevations in serum ALT and AST (often to above 2000 U/L), followed at 48 to 96 hours by clinical symptoms: jaundice, confusion, hepatic failure and in some instances death

IHC analyses were therefore performed in order to examine the relative expression levels of TH in the hippocampal tissues of the mice

However, doxorubicin induces mitochondrial dysfunction, this might be due to increased nitric oxide production, accumulation of iron in mitochondria, and ROS production due to futile redox cycling (42)