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In some clinical protocols, these peptides are combined or alternated

In the cardiovascular context, DAMPs release from ferroptotic cardiomyocytes or endothelial cells activates resident macrophages, recruits circulating monocytes and neutrophils, and stimulates the production of inflammatory cytokines such as tumor necrosis factor- (TNF-), interleukin-1 (IL-1), and interleukin-6 (IL-6)