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doi: 10.1007/978-94-007-2199-9_7 25 LauerAAGrimmHSApelBGolobrodskaNKruseLRatanskiEet al

Therefore, the use of genetically engineered cells with human CYP overexpression or HepaRG cells with stable metabolic competence, low batch-to-batch differences and the potential to form bile canaliculi and functional tight junctions might represent more valuable, practical alternatives for genotoxicity screening of NAs, as recently reported (Carlsson et al

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Results from a 16-week study suggest that the CJC-1295 analog may influence the growth hormone and IGF-1 levels