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A clinical series published in the Journal of Clinical Medicine found that patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) who received intermittent intravenous saline infusions over a 9-week period showed beneficial effects in managing symptoms of dysautonomia and postural orthostatic tachycardia syndrome (POTS)

It also provides a valuable methyl donor, aiding in detoxification

ADVERSE REACTIONS Adults In two randomized clinical studies [Studies 1 and 2], a total of 1775 patients were exposed to Injectafer, 15 mg/kg of body weight, up to a maximum single dose of up to 750 mg of iron on two occasions, separated by at least 7 days, up to a cumulative dose of 1500 mg of iron

Unnecessary supplementation may mask other underlying causes of fatigue or health concerns

[] Abbreviations CT Computed Tomography DRG Dorsal root ganglion HZ Herpes zoster LTD Long-term depression MeCbl Methylcobalamin OCI Obliquus capitis inferior PHN Postherpetic neuralgia PRF Pulsed radiofrequency RF Radiofrequency VAS Visual Analog Scale Importantly, C2 dorsal root ganglion (DRG) PRF may be performed under ultrasound, fluoroscopy, or computed tomography (CT) guidance