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The miR-522 inside exosomes, generated from cancer-associated fibroblasts (CAFs), can block lipid-ROS accumulation by targeting ALOX15 and thus inhibit ferroptosis (Zhang H

The first mammalian regulator of apoptosis emerged when bcl-2 , the gene activated by chromosome translocation in human follicular lymphoma [131] was unexpectedly found to permit the survival of cytokine-dependent hematopoietic cells, in a quiescent state in the absence of exogenous cytokine [132]

Some miRNAs, such as miR-489-3p and miR-375, can directly target SLC7A11 and trigger ferroptosis (Ni H

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Carotenoids are good scavengers of ROS including singlet oxygen and therefore can alleviate oxidative stress in patients with AD