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Intervention Strategies and Clinical Trials For patients who meet the surgical standards, posttraumatic intracranial hematoma (TICH) removal can reduce the neurotoxic effect of iron released by lysis from red blood cells (Tao et al., 2017) and prevent the occurrence of cerebral hernia caused by the increase in intracranial pressure (Table 1)

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Long-term safety, tolerability, and weight loss associated with metformin in the Diabetes Prevention Program Outcomes Study Diabetes Care 35 4: 731-7