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Cytoprotection by prostaglandins in rats: prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury

Absence of expected improvement by mid-protocol (4-6 weeks) warrants reassessment

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Hypothesis 4 Body composition Retatrutide's glucagon-receptor activation drives some of its weight loss through increased energy expenditure, which is mechanistically associated with sparing more lean mass than pure-satiety pathways