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Martin-SanchezDRuiz-AndresOPovedaJCarrascoSCannata-OrtizPSanchez-NioMDet al

If concomitant use is warranted, consider recommending or prescribing an opioid overdose reversal agent (see WARNINGS, Life-Threatening Respiratory Depression

DAI often occurs after TBI and is characterized by a loss of consciousness and extensive axonal damage to the cerebral hemispheres, cerebellum and brainstem

Studies have revealed a correlation between low glutathione levels and damage to neurons that manufacture dopamine, suggesting a link to Parkinsons disease