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249 A further population-based cohort study discovered that patients with MDD had much higher prevalence and incidence rates of chronic liver disease than the general population

conducted a large, population-based longitudinal cohort study, establishing a link between increased TG levels and a heightened risk of depression ( Figure 1E ), in individuals with major depression

In fact, the gut microbiota can regulate glucose metabolism by regulating the interaction between BAs and FXR and TGR5 signaling [112]

Our findings suggest that this combinatorial treatment could be an effective and novel therapeutic strategy for recurrent OV