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Comprehensive lipidomic profiling of FRDA patient-derived fibroblasts has demonstrated a profound pathological remodeling of the lipidome that directly predicts disease severity [104]

Bhasin S

Fermentation 6:23

[DOI] [PubMed] [Google Scholar] 248

Exploration of intra-hepatic changes after APAP overdose in humans can only be studied using in vitro cell culture approaches, due to the lack of liver biopsies from these patients where the procedure is contraindicated