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An siRNA approach has also been applied to circulating angiogenic cells and showed that a 50% silencing of the GLA gene is enough to significantly impact their migration capacity [58] To shed light on the mechanism by which -Gal A deficiency leads to another commonly observed Fabry disease phenotype, namely neuronal dysfunction, Kaneski et al

The trial identifier is NCT07437547

Giorgio C, Zippoli M, Cocchiaro P et al (2021) Emerging role of C5 complement pathway in peripheral neuropathies: current treatments and future perspectives

Ethacrynic acid and its glutathione conjugate as inhibitors of glutathione S-transferases

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