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Apoptosis 11(6):889-904, 2006

The ability of a quinone to redox cycle is dependent upon the favourability of its reduction by a single electron, which can be quantitatively described by its reduction potential ( E o )

On the contrary, in cancer cells, PI3K/Akt signaling cascade enhances cell proliferation, and decreases chemotherapeutic responsiveness

Author contributions WA: Data curation, Formal Analysis, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing original draft, Writing review & editing