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however, it does not fundamentally alter the progression of the disease (Jayaram et al., 2023

Genomics 300 (1), 12

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Moreover, SeNPs exhibit antioxidant activity with less toxic effects than zero-valent selenium (Se 0 ) [51] or sodium selenite [155]

Similarly, an open-label Phase 1 pilot study (NCT02848131) in patients with diabetic kidney disease showed that the combination of quercetin and dasatinib can eliminate senescent cells and significantly reduce senescent cell burden in adipose and skin tissues within 11 days