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[52] intranuclear accumulation of glutathione may modulate the thiol/disulfide redox status of nuclear proteins and control chromatin compacting and decondensation

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Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation

Concerning statins, studies have demonstrated their anti-tumour effects in several cancer [15, 72] including on melanoma as single drug [13, 16] or in combination with cisplatin [73]