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In neurons, lactate is converted into pyruvate by lactate dehydrogenase 1, which then enters the TCA cycle and undergoes oxidative phosphorylation, resulting in the production of significant amounts of ATP to meet the energy demands of normal physiological activities

Further confirmation was obtained in an isoproterenol-induced myocardial infarction mouse model, where these two LTB4DH inducersnamely calycosin and GAsignificantly reduced the levels of myeloperoxidase (MPO) and MDA in cardiac tissues, thereby attenuating the cardiac morphological changes induced by isoproterenol (Cheng et al., 2015)

Vetrano DL Article: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

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