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Description

Since activation pathway of HIV gene expression by cellular transcription factor NFKB conceptually precedes activation by viral trans- activators, it is conceptual to ascribe NFKB as a determinant of the maintenance and breakdown of the viral latency

Journal of Insurance Medicine (New York, NY) [Internet] 2012

IMGN853 (mirvetuximab soravtansine) is an antibody-drug conjugate (ADC) comprised of the chimeric anti-FR M9346A antibody, a humanized derivative of the previously described anti-FRa antibody Mov19 [49] linked to the tubulin-disrupting maytansinoid, DM4, via a sulfo-SPDB linker