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Dabigatran is a P-gp substrate but is not metabolized by CYP3A4, so the pharmacokinetic concern would be limited to P-gp

Consequently, the focus on low body weight is essential to improve LACC outcomes [34]

Next, we measured the mitochondrial oxygen consumption rate (OCR) under both normoxic and hypoxic conditions in the cybrids, as OCR is a key indicator of mitochondrial function