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197 Six years later, two studies on the identification of nonhistone protein crotonylation have been developed by using the pan lysine crotonylation (-Kcro) antibody and LCMS/MS

Variants in TP53 (rs1042522), particularly the Pro allele, are linked to impaired apoptotic function and heightened NPC risk, while MDM2 (rs2279744) facilitates p53 degradation, further driving tumor progression (31)

In further embodiments, the invention encompasses a method of providing muscular therapy by contacting a cell expressing NNMT with one or more cations chosen from Tables 1, 2, 3a, and 3b

Food Chem Toxicol 173:113631

doi: 10.1021/acs.bioconjchem.8b00546