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165 Oral nano-silica for 12 weeks leads to gut flora dysbiosis, metabolite imbalance, and gut barrier damage in mice, causing liver-specific silicon accumulation, which subsequently triggers hepatic lipid deposition, senescence, and fibrosis via the microbegutliver axis

Decreased ventrolateral PFC activity is another common feature of bipolar mania that differentiates it from depressed, euthymic state, and healthy controls (99, 105, 106, 137)

Dual inhibition of reactive oxygen species and spleen tyrosine kinase as a therapeutic strategy in liver fibrosis