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Recently, alterations in the genes SQSTM1, CSF1, OPTN, TNFRSF and TM7SF4 7,8 , have been associated with a higher risk of developing PDB

doi:10.1038/s41591-020-0751-5 29

Fc receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2

PMID: 149 SrivastavaNHuHPetersonOJVomundANStremskaMZamanMet al

The mitochondrial iron pool, which is normally tightly regulated for heme synthesis and iron-sulfur cluster assembly, becomes labile during ferroptosis, driving ROS production and contributing to energy failure [57]