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Theoretically, yes, through two mechanisms

High blood pressure, atherogenic cholesterol particles, elevated blood sugar, smoking, chronic kidney disease, inflammation, inactivity, poor sleep, and genetic factors may accelerate vascular damage

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doi: 10.1006/taap.2000.9107

Springer, pp 709732." Parascandolo A, Laukkanen MO, De Rosa N, Ugolini C, Cantisani MC, Cirafici AM, Basolo F, Santoro M, Castellone MD (2018) A dual mechanism of activation of the Sonic Hedgehog pathway in anaplastic thyroid cancer: crosstalk with RAS-BRAF-MEK pathway and ligand secretion by tumor stroma