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168 The consensus among experts is that due to the deleterious effect that elevated homocysteine levels has on both Parkinson's itself and L-DOPA therapy, supplementation with folate, B6, and B12 is warranted

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Even if crystals form, internal motions within the protein can lead to averaged electron density maps, blurring out the finer details and limiting the resolution of the determined structure (Hekstra, 2023)