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The original Achilles tendon transection model in rats (Staresinic, Sikiric et al., 2003) showed that systemic BPC-157 accelerated healing of fully transected tendons, and this finding has been reproduced across multiple labs over the 20+ years since

in rats with abdominal aorta anastomosis BPC 157 both prevents thrombotic clot formation and destroys already formed thrombosis (40) and also, after amputation, BPC 157 reduces bleeding time and thrombocytopenia after heparin, warfarin or aspirin administration (41)

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Additionally, the rapid therapeutic effect of BPC 157 is evidenced by rapid reversal of the negative chain of events (Vukojevic et al., 2018)