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Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b

After co-incubation for 6 h, the cells were collected by centrifugation

In a phase 2 randomized open-label clinical trial, selonsertib was shown to reduce the extent of liver fibrosis in patients with NASH and stage 23 fibrosis (Peeraphatdit et al., 2018