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Tirzepatide and retatrutide (single molecule): A single engineered molecule that hits multiple receptors simplifies the formulation to one compound with one pharmacokinetic profile, and allows the balance of receptor activation to be tuned at the molecular-design level

Wild-type WD40 with wild-type S hepta-peptide grew in 0.1 M MES pH 6.2, 19% PEG 4000

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