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In colorectal CSCs, knockdown or inhibition of SLC7A11 significantly and specifically kills cancer cells and thus attenuates chemoresistance in CRC (Xu et al., 2020c)

Antibodies: Affinity-purified, HRP-conjugated, rabbit anti-GST antibody 18844P used for WB at 0.2 g/ml (1:5,000)

Then, the solution was stirred for 1 h

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Direct effects of ROS, generally attributed to high concentrations at the site of damage, include DNA strand breaks, point mutations, aberrant DNA cross-linking, and mutations in proto-oncogenes and tumor-suppressor genes, thus promoting neoplastic transformation [7, 95]