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10.1002/ame2.12227 126 ZhouZ.ZhongW.LinH.HuangP.MaN.ZhangY.et al (2017)

L.TomaW.BagdasD.MeadeJ

Cell 144:646674

Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy

[32], activation of this pathway suppresses pro-inflammatory cytokine production via NF-B inhibition and promotes the synthesis of prostaglandin D2, which in turn further attenuates NF-B signaling and associated inflammatory cascades [40]