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Glycine betaine is the result of a two-step oxidation of choline by betaine aldehyde which is a toxic intermediate ( + dependent betaine dehydrogenase (BADH) ( in vivo varies among plant species and is between 40 and 400 mol g-1 (DW) in natural accumulation under stress conditions (Wani et al., 2013)

The nerve becomes over-sensitive , so even small triggers like light touch, clothing, a breeze, or stress can hurt

If your goal is genuine RF microneedling results, the right route is a board-certified dermatology or aesthetic clinic, before any device purchase

10.1007/s11556-009-0047-8 260 SartoriusA.HellwegR.LitzkeJ.VogtM.DormannC.VollmayrB.et al (2009)

2011;3(73):73ra19