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Both staurosporine and calphostin, an inhibitor of classic and novel PKC isoforms, block hyperglycemia-induced NF- B activation [92, 260], and a specific PKC inhibitor (ruboxistaurin) prevents AGEs-induced ICAM-1 expression and leukocyte adhesion in HUVECs [261]

The significance of hypothiocyanite production via the Pendrin/DUOX/Peroxidase pathway in the pathogenesis of asthma

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Current research has demonstrated the critical function of chemicals released by activated microglia in triggering reactive astrocytosis and controlling astrocytic immune responses