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Neither of which were measured in the trial by Madeo et al., but it could be observed in two studies by Paoli et al

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The induction of protective cellular pathways, such as those involving vitagenes like sirtuins (a class of HDACs), has been proposed as a related neuroprotective strategy observed in other auditory pathologies like Menieres disease, which is characterized by tinnitus and considered a model of cochlear neurodegeneration (Scuto et al., 2020)

It is generally considered safe to consume through food when glutathione, naturally produced by the body, is not sufficient

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