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Pereira SR, Pereira R, Figueiredo I, Freitas V, Dinis TCP, Almeida LM

Although many pathological stimuli can trigger necroptosis, the most typical pathway for inducing necroptosis is TNF and FAS signaling, in which CASP8 inhibition activates necrosomes (a multi-protein complex containing RIPK1, RIPK3, and MLKL) to trigger necroptosis [113]

The blood was centrifuged at 3,000 g for 10 min at 4 C and the serum was collected and stored at 80 C

Carotenoids have antioxidant action because they quench singlet oxygen radicals, preventing photo-oxidative damage to the plant