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therefore, OG has the potential to decrease sebum output.[32] Further, when evaluated in animal models, topical OG consistently reduced sebaceous gland size.[33] While this molecule was designed to inhibit sebum production following topical application, per Dermiras website, none of the primary endpoints for the trials directly evaluated sebum output or the appearance of oily skin

It sits in a group of treatments known as skin boosters, which a research review describes as a wide array of ingredients employed to enhance and improve skin condition when placed into the skin, marking a shift away from using injectables purely to plump one area, as noted in this skin booster classification paper

In addition they also reduce ATP production, leading to cancer cell death

Roles and mechanisms of choline metabolism in nonalcoholic fatty liver disease and cancers