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Thus, intermittent fasting is most often used by people who: they live an irregular lifestyle, they do not want to count calories and follow a specific nutritional plan, they used low-energy diets, but did not achieve the desired effect, they have a problem with the evening snacking and do not feel hunger from the morning, they want to lose weight without giving up their favourite foods

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Hypothalamic and Hormonal Disruption MSG crosses the blood-brain barrier and affects the hypothalamus, the brain region that regulates: Hunger and satiety Reproductive hormones Stress and cortisol balance Rodent studies have shown that MSG exposure in early life causes obesity, infertility, and disrupted HPA axis signaling later in life

Ferreira I, de Sousa Melo D, Menezes AGT et al (2022) Evaluation of potentially probiotic yeasts and Lactiplantibacillus plantarum in co-culture for the elaboration of a functional plant-based fermented beverage

Additionally, metformin inhibits mitochondrial respiratory chain complex I, which lowers proton leak and ROS generation in hepatocyte mitochondria, thereby reducing hepatocyte apoptosis to treat DILI (99)