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High visceral fat is strongly associated with: Type 2 diabetes Cardiovascular disease Fatty liver disease Hypertension Cognitive decline Increased all-cause mortality Even individuals with a normal body mass index may carry excess visceral fat, a phenomenon often referred to as TOFI (thin outside, fat inside)

Yang W, Chen YH, Liu H, Qu HD (2015) Neuroprotective effects of piperine on the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsons disease mouse model

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Mice of desired strains were age-matched and assigned randomly to their treatment groups