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Description

PKM2 not only accelerates cytoplasmic glycolysis (increasing lactate production by 22%) but also translocates to the nucleus to synergize with HIF-1 in upregulating glycolytic genes

Immunomodulatory Effects of Glutathione and Vitamin C on Gut Mucosal Immunity

Cell 148 , 765779 (2012)

Through these mechanisms, the fermentation activity of Bifidobacterium and Lacticaseibacillus not only supports nutrient utilization and gut barrier integrity but also contributes to systemic health benefits in the host