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This randomized, placebo-controlled, double-blind study in healthy adults (ages 21-61) demonstrated that subcutaneous administration of CJC-1295 (DAC) led to sustained, dose-dependent increases in mean plasma GH concentrations (2- to 10-fold for 6 days or more) and IGF-I concentrations (1.5- to 3-fold for 9-11 days)

sKlotho is also produced by alternative Klotho mRNA splicing (Xu and Sun, 2015)

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Oral supplements can help to improve the overall health and appearance of the skin, while topical products can target specific areas of concern, such as dry patches or acne-prone areas

doi: 10.1021/acsomega.2c00083 177 TangYKangY