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His Royal Highness also introduced the habit of smoking cigarettes immediately after the conclusion of dinner, while the port was circulating, thus ending a rigid rule that a gentlemans clothes must not be tainted by the noxious weed. Feminine opposition was gradually worn downto such good purpose, indeed, that by the end of the nineteenth century the ladies themselves had fallen under the spell of the cigarette. Tobacco: The History of a Habit Benson and Hedges Ltd

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All marine species have become mutants due to ocean pollution and as a result of climate change

How these structural defects affect the fibril stability and make the mutant peptides more prone to degradation remain to be fully evaluated

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