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Stress doesn't directly cause stroke, but it can cause dangerous surges in your blood pressure, as well as heart rhythm changes or blood vessel spasms that can increase your risk for both ischemic and hemorrhagic strokes

4 In addition to an increased risk of cancer, smoking raises the probability of stroke, respiratory diseases and inflammation, and weakens immune functions

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After looking at nearly 16,000 people, they found that smokers had methylation changes affecting more than 7,000 genes (which is 1/3 of the human genome)

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