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Its necessity and importance in medicine research confirm e.g

Thus, by utilising antioxidants that target Klf9, premalignant cancer cells proliferation can be suppressed [43, 44]

SIRT1, an NAD + -dependent deacetylase, regulates multiple critical processes, including lipid metabolism reprogramming, insulin signaling, oxidative stress response, autophagy, and immune balance, forming a regulatory network that spans metabolic, inflammatory, immune, and stress-related pathways