Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-Exatecan Size:25mg Product Name Thalidomide-O-PEG4-C2-amine HCl Synonyms

Product Name Thalidomide-O-PEG4-C2-amine HCl Synonyms Thalidomide-4'-O-PEG4-C2-amine HCl CAS Number 2820929-03-9 Related CAS 2401832-00-4 (free base) Molecular Formula C23H32ClN3O9 Molecular Weight 529

Product Name N'-Formylkynurenine Synonyms CAS Number 1022-31-7 Related CAS Molecular Formula C11H12N2O4 Molecular Weight 236

The conjugates of TMR C2 maleimides have the identical excitation and emission wavelengths at 544/572 nm to those of tetramethylrhodamine maleimides or iodoacetamide

Product Name [(4-bromophenyl)methyl]((methyl-d3))amine Synonyms [(4-bromophenyl)methyl]((²H3)methyl)amine CAS Number n/a Related CAS Molecular Formula C8H10BrN Molecular Weight 203

376 SMILES OC(=O)C1CCN(CC1)C1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-Exatecan Size:25mg Product Name Thalidomide-O-PEG4-C2-amine HCl SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I